All This Protection in Just One Monthly Chewable

Simparica Trio is the first monthly chewable to protect your dog with three proven ingredients designed for defense.

  • Protects dogs against heartworm disease, ticks & fleas, roundworms & hookworms.
  • Demonstrated safe for puppies as young as 8 weeks old, weighing at least 2.8 lbs.
  • FDA-approved and available with a vet’s prescription.
  • 100% satisfaction guaranteed.

Try Simparica Trio and earn up to $80 in rewards!

It’s Time to Enhance Your Dog’s Protection

Enhance Your Dog's Protection
  • Just 1 monthly Simparica Trio chewable provided 100% protection in a study.
  • The only chewable proven to kill 5 types of ticks. Competitive chewable brands are only approved to kill 4.*
  • Prevents flea infestation by killing fleas before they can even lay eggs. Starts killing within 4 hours, and achieved 100% effectiveness in 8 hours in a study.
  • Treats and controls roundworms and hookworms to protect your dog from intestinal parasites.

*Bravecto®, NexGard®, and Credelio® are approved to kill only four types of ticks.

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Why Your Dog Needs Protection

See why it’s so important to protect your best friend.

Frequently Asked Questions

Important Safety Information: Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information.


  1. AHS Canine Guidelines 2018.
  2. Centers for Disease Control and Prevention. Geographic distribution of ticks that bite humans. Updated June 1, 2015. Accessed March 19, 2019.
  3. Companion Animal Parasite Council. Ticks. April 12, 2017. Accessed September 10, 2019.
  4. Byron L. Blagburn, BS, MS, PhD.*, Michael W. Dryden, DVM, PhD. Biology, Treatment, and Control of Flea and Tick Infestations. 2009; 4.
  5. Flea Allergy Dermatitis in Cats and Dogs. VetStreet website. Updated Apr 22, 2014. Accessed Mar 21, 2019.

Bravecto is a registered trademark of Intervet Inc., d/b/a Merck Animal Health. NexGard is a registered trademark of Boehringer Ingelheim Animal Health USA Inc. Credelio is a registered trademark of Elanco or its affiliates.