Simparica

Why Simparica?

Protects dogs from ticks and fleas for 35 days¹
Stays strong all month long, unlike some other products^2-6
Starts killing ticks and fleas fast^7†
Only monthly tick and flea chewable approved to kill 5 types of ticks, including the Gulf Coast tick
In a study, Simparica blocked transmission of Lyme disease from deer ticks to dogs^8‡
FDA-approved and available at the vet’s office
Great-tasting chewable you give your dog once a month
Earn up to $35 in rewards with your Simparica purchase*

^†Studies show that Simparica starts killing fleas in 3 hours and ticks in 8 hours.⁷

^‡In a study, Simparica was shown to kill >98% of existing deer tick infestations within 12 hours. Lyme disease is typically transmitted in 24-48 hours.⁸

The Simparica Difference: no dropoff in effectiveness at the end of the month, unlike some other products^2‑6

Ticks and fleas don’t slow down at the end of the month. Your dog’s tick and flea protection shouldn’t either. Simparica starts—and stays—strong all month long.¹

In a study, Simparica killed more brown dog ticks than NexGard

24 hours after infestation at day 28³

: 24-hour study results

In a study, Simparica killed more brown dog ticks than NexGard

24 hours after infestation at day 28³
: 48- to 72-hour comparison

Comparison of the effectiveness of Simparica and NexGard against ticks 48-72 hours after infestation⁹

In a study, Simparica killed more fleas than NexGard

8 hours and 12 hours after flea infestation at day 28²

On day 28, NexGard performed above 90% starting at 12 hours, taking 4 more hours to match Simparica’s results. After 24 hours, NexGard caught up completely to Simparica, demonstrating 100% effectiveness at all time points.²

NexGard is a registered trademark of Merial.

Satisfaction Guarantee

FLEAS
TICKS
LYME DISEASE

We want you to be 100% satisfied with Simparica. We’ll work with you to make sure you’re satisfied with Simparica’s performance. If for any reason you’re still not completely happy, we’ll send you a replacement or give you your money back. Simply give us a call at 1‑888‑ZOETIS1 and we’ll take care of you.

Download complete Satisfaction Guarantee

Ticks and fleas—small pests, big problem

Ticks and fleas can bug your dog year-round.¹⁰ Some can even put your dog’s health in danger.¹¹

Facts about ticks

Ticks can be found anywhere in the US and at any time of year¹⁰
It just takes 1 infected tick to spread disease that can be harmful, even deadly, to dogs^12,13
Some ticks can survive freezing temperatures and become active when the temperature rises to 40°F^14,15

Simparica is the ONLY monthly tick and flea chewable approved to kill 5 types of ticks. It starts working fast* and goes strong for 35 days.¹ In a study, Simparica blocked transmission of Lyme disease from deer ticks to dogs.^7†

Ticks are a growing problem

Animated map of ticks in the United States

*Studies show that Simparica starts killing fleas in 3 hours and ticks in 8 hours.⁸
^†In a study, Simparica was shown to kill >98% of existing deer tick infestations within 12 hours. Lyme disease is typically transmitted in 24–48 hours.⁷

Facts about fleas

Where there’s one flea, there can be hundreds more
It only takes 1 “pregnant” flea to infest your dog or home
Fleas can carry diseases that make your dog sick
Some dogs are allergic to fleas, and symptoms like skin inflammation, hair loss, and sores can make dogs miserable¹⁶

Monthly Simparica starts killing fleas fast* (before they can lay eggs), and it goes strong for 35 days. Simparica provides much-needed, fast relief for dogs with fleas and dogs with flea allergies.

Protect your home from fleas

*Studies show that Simparica starts killing fleas in 3 hours and ticks in 8 hours.⁸

Remind me about Simparica dosing

To make sure your dog is always protected from ticks and fleas, it’s important to give your dog their tasty Simparica chewable at the same time every month.

We offer free monthly reminder emails and/or text messages to help you remember when it’s time for the next dose.

Sign up for Monthly Reminders

How is Simparica different from other tick and flea chewables?

See the Simparica Difference:

The only monthly tick and flea chewable for dogs approved to kill fleas and 5 types of ticks, including the Gulf Coast tick
No dropoff in effectiveness at the end of the month, unlike some other products^2-6

How often do you give Simparica?

Give a Simparica chewable to your dog once a month.

How long does Simparica protection last?

Simparica is a monthly chewable that starts protecting in hours* and lasts for 35 days.¹ That gives you a little wiggle room at the end of the month, in case you’re late with the next month’s dose.

How long does it take Simparica to kill ticks and fleas?

Simparica starts killing ticks and fleas fast. Simparica starts killing fleas within 3 hours and ticks within 8 hours.⁸

What types of ticks does Simparica kill?

Simparica is the only monthly tick and flea chewable for dogs approved to kill 5 types of ticks, including the Gulf Coast tick:

Gulf Coast tick
Brown dog tick
Deer tick/black-legged tick
American dog tick
Lone Star tick

Can Simparica help prevent Lyme disease?

In a study, Simparica blocked transmission of Lyme disease from deer ticks to dogs.⁷*

*In a study, Simparica was shown to kill >98% of existing deer tick infestations within 12 hours. Lyme disease is typically transmitted in 24-48 hours.⁷

What if I’m late with a Simparica dose?

Simparica is a monthly chewable that protects your dog for 35 days.¹ That means you have a little wiggle room at the end of the month. If you have questions about dosing, talk to your vet.

We understand it can be hard to stay on top of your dog’s dosing schedule. That’s why we offer free monthly reminder emails and/or text messages. Get monthly reminders.

Do I have to give Simparica with food?

No, unlike some other treatments, Simparica can be given with or without food.

Do I need a prescription for Simparica?

Yes, Simparica is available only by prescription from your vet. Talk to your vet today about Simparica. If you don’t have a vet, we can help you find a veterinarian.

What is the Zoetis Petcare Rewards program and how can I earn rewards with my Simparica purchase?

Zoetis Petcare Rewards is a program designed to help you save on pet care at your veterinarian.^† Whenever you purchase an eligible Simparica product, you can submit an invoice to earn points. Points can be redeemed for a Zoetis Petcare Rewards Mastercard to use at your veterinarian for any product or service. See Simparica offers.

What is the Simparica Satisfaction Guarantee?

We want you to be completely satisfied with Simparica. We’ll work with you to make sure you’re satisfied with Simparica’s performance. If for any reason you’re still not completely happy, we’ll send you a replacement or give you your money back. Simply give us a call at 1‑888‑ZOETIS1 and we’ll take care of you.

*Studies show that Simparica starts killing fleas in 3 hours and ticks in 8 hours.⁸

^†Program Terms and Conditions apply.

References:

Six RH, Everett WR, Young DR, et al. Efficacy of a novel oral formulation of sarolaner (Simparica™) against five common tick species infesting dogs in the United States. Vet Parasitol. 2016;222:28-32.
Six RH, Liebenberg J, Honsberger NA, Mahabir SP. Comparative speed of kill of sarolaner (Simparica™) and afoxolaner (NexGard®) against induced infestations of Ctenocephalides felis on dogs. Parasit Vectors. 2016;9:90.
Six RH, Young DR, Holzmer SJ, Mahabir SP. Comparative speed of kill of sarolaner (Simparica™) and afoxolaner (NexGard®) against induced infestations of Rhipicephalus sanguineus s.l. on dogs. Parasit Vectors. 2016;9:91.
Six RH, Liebenberg J, Honsberger NA, Mahabir SP. Comparative speed of kill of sarolaner (Simparica™) and fluralaner (Bravecto®) against induced infestations of Ctenocephalides felis on dogs. Parasit Vectors. 2016;9:92.
Becskei C, Geurden T, Liebenberg J, Cuppens O, Mahabir SP, Six RH. Comparative speed of kill of oral treatments with Simparica™ (sarolaner) and Bravecto® (fluralaner) against induced infestations of Rhipicephalus sanguineus on dogs. Parasit Vectors. 2016;9:103.
Six RH, Everett WR, Myers MR, Mahabir SP. Comparative speed of kill of sarolaner (Simparica™) and spinosad plus milbemycin oxime (Trifexis®) against induced infestations of Ctenocephalides felis on dogs. Parasit Vectors. 2016;9:93.
Six RH, Geurden T, Carter L, et al. Evaluation of the speed of kill of sarolaner (Simparica™) against induced infestations of three species of ticks (Amblyomma maculatum, Ixodes scapularis, Ixodes ricinus) on dogs. Vet Parasitol. 2016;222:37-42.
Honsberger NA, Six RH, Heinz TJ, et al. Efficacy of sarolaner in the prevention of Borrelia burgdorferi and Anaplasma phagocytophilum transmission from infected Ixodes scapularis to dogs. Vet Parasitol. 2016;222:67-72.
NexGard [package insert], Duluth, GA: Merial; 2015.
Centers for Disease Control and Prevention. Geographic distribution of ticks that bite humans. http://www.cdc.gov/ticks/geographic_distribution.html. Updated June 1, 2015. Accessed March 19, 2019.
Blagburn BL, Dryden MW. Biology, treatment, and control of flea and tick infestations. Vet Clin Small Anim. 2009;39(6):1173-1200.
How ticks spread disease. Centers for Disease Control and Prevention website. https://www.cdc.gov/ticks/life_cycle_and_hosts.html. Updated January 10, 2019. Accessed March 19, 2019.
Little SE. Changing paradigms in understanding transmission of canine tick-borne diseases: the role of interrupted feeding and intrastadial transmission. In: Proceedings of the 2nd Canine Vector-Borne Disease (CVBD) Symposium; April 25-28, 2007; Sicily, Italy.
Fleas, ticks & your pet. Companion Animal Parasite Council (CAPC) website. http://www.petsandparasites.org/images/uploads/documents/BC-3844_CAPC_FleaTick_one-color_04.pdf. Updated March 2011. Accessed March 25, 2019.
Ticks: What are the risks in northern New England? University of Vermont Medical Center website. https://medcenterblog.uvmhealth.org/infectious-disease/ticks-northern-new-england. Updated August 23, 2018. Accessed March 25, 2019.
Flea Allergy Dermatitis in Cats and Dogs. Vet Street website. http://www.vetstreet.com/care/flea-allergy-dermatitis-in-cats-and-dogs. Updated April 22, 2014. Accessed March 21, 2019.

SMP-00277R2

Monthly Simparica protects dogs from ticks and fleas for 35 days¹

Earn up to $35 in rewards from your Simparica purchase*

Why Simparica?

Earn up to $35 in rewards with your Simparica purchase*

How it works

Fetch this reward and bring it to your vet

The Simparica Difference: no dropoff in effectiveness at the end of the month, unlike some other products^2‑6

In a study, Simparica killed more brown dog ticks than NexGard

In a study, Simparica killed more brown dog ticks than NexGard

Comparison of the effectiveness of Simparica and NexGard against ticks 48-72 hours after infestation⁹

In a study, Simparica killed more fleas than NexGard

On day 28, NexGard performed above 90% starting at 12 hours, taking 4 more hours to match Simparica’s results. After 24 hours, NexGard caught up completely to Simparica, demonstrating 100% effectiveness at all time points.²

Satisfaction Guarantee

Ticks and fleas—small pests, big problem

Ticks are a growing problem

Protect your home from fleas

Remind me about Simparica dosing

Simparica Frequently Asked Questions

References:

Monthly Simparica protects dogs from ticks and fleas for 35 days1

Earn up to $35 in rewards from your Simparica purchase*

Why Simparica?

Earn up to $35 in rewards with your Simparica purchase*

How it works

Fetch this reward and bring it to your vet

The Simparica Difference: no dropoff in effectiveness at the end of the month, unlike some other products2‑6

In a study, Simparica killed more brown dog ticks than NexGard

In a study, Simparica killed more brown dog ticks than NexGard

In a study, Simparica killed more fleas than NexGard

On day 28, NexGard performed above 90% starting at 12 hours, taking 4 more hours to match Simparica’s results. After 24 hours, NexGard caught up completely to Simparica, demonstrating 100% effectiveness at all time points.2

Satisfaction Guarantee

Ticks and fleas—small pests, big problem

Remind me about Simparica dosing

References:

Monthly Simparica protects dogs from ticks and fleas for 35 days¹

The Simparica Difference: no dropoff in effectiveness at the end of the month, unlike some other products^2‑6

On day 28, NexGard performed above 90% starting at 12 hours, taking 4 more hours to match Simparica’s results. After 24 hours, NexGard caught up completely to Simparica, demonstrating 100% effectiveness at all time points.²