Dr. Chris Adolph, Senior Veterinary Specialist (Parasitology) at Zoetis, spoke with the New York Times Wirecutter as they sought out to review the best flea and tick treatments for cats and dogs. The staff looked at 20 treatments and picked their top four for dogs and cats with Simparica Trio® (sarolaner, moxidectin, and pyrantel chewable tablets) and Revolution Plus® (selamectin and sarolaner topical solution) making the list.
Simparica Trio is featured as Wirecutter’s top pick for dogs noting that it offers “the broadest protection for the lowest price.” Revolution Plus is featured as the runner-up for cats noting that it prevents four types of ticks including lone star tick and the Gulf Coast tick.
Important Safety Information
Simparica Trio
Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information.
Revolution Plus
The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Revolution Plus contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions, such as tremors, ataxia, and seizures in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes See full Prescribing Information.
