woman posing for photo with dog

How Apoquel is Different From Other Treatments

Apoquel has been prescribed for over 12 million dogs1 and is #1 in dog owner and vet satisfaction.2,3*

  • Antihistamines offer little or no benefit in treating flare-ups in a majority of dogs with allergic itch.4
  • Apoquel can be used for short-term5 treatment or long-term6 management.
  • Oatmeal baths, lotions, or over-the-counter topical medicines may provide some temporary relief but don’t get to the underlying cause of allergic itch.

Important Safety Information: Do not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. See Prescribing Information.

Indications: Control of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

*Based on survey data from veterinarians (n=251) and pet owners (n=552).


  1. ZMR: GAH-284 Unique Patients Since Launch with Growth Rate June 2022
  2. Data on file, APOQUEL/CYTOPOINT Pet Tracker Wave 9, 2021, Zoetis Inc.
  3. Data on file, APOQUEL/CYTOPOINT Vet Tracker Wave 13, 2020, Zoetis Inc.
  4. Olivry T, DeBoer DJ, Favrot C, et al; for the International Committee on Allergic Diseases of Animals. Treatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA). BMC Vet Med Assoc. 2015;241(2):194-207.
  5. Gadeyne C, Little P, Edwards N, et al. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014;25:512-e86.
  6. Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26:171-179.
  7. Gonzales AJ, Bowman JW, Fici G, et al. Oclacitinib (APOQUEL®) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. J Vet Pharmacol Ther. 2014;37(4):317-324.