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Pest Protection Simparica Trio (sarolaner, moxidectin, and pyrantel chewable tablets)
Prevents heartworm disease dark green checkmark
Kills 5 types of ticks dark green checkmark
Kills fleas dark green checkmark
Kills fleas before they can lay eggs dark green checkmark
Treats roundworms dark green checkmark
Treats hookworms dark green checkmark

Approved for Dogs
8 Weeks+

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Approved for Dogs
2.8lbs+

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IMPORTANT SAFETY INFORMATION: Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information.

References:

  1. Heartgard® Plus [package insert], Duluth, GA: Boehringer Ingelheim Group; 2018
  2. NexGard® [package insert], Duluth, GA: Boehringer Ingelheim Group; 2019.
  3. Bravecto® [package insert], Summit, NJ: Merck & Co; 2019.
  4. Credelio® [package insert], Greenfield, IN: Elanco; 2017.
  5. Interceptor® Plus [package insert]. Greenfield, IN: Elanco; 2020.
  6. Trifexis® [package insert], Greenfield, IN: Elanco; 2020.

Heartgard and NexGard are registered trademarks of Boehringer Ingelheim Animal Health USA Inc. Bravecto is a registered trademark of Intervet Inc. d/b/a Merck Animal Health. Credelio, Interceptor, and Trifexis are registered trademarks of Elanco or its affiliates.

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The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or may have different product labeling in different countries. The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient. Sileo® is trademark owned by Orion Corporation Orion Pharma Animal Health. It is manufactured by Orion Corporation and distributed by Zoetis under license from Orion Corporation Orion Pharma Animal Health.

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